title:: New concepts for mitral valve imaging
publisher:: AME Publishing Company
people:: Thilo Noack, Philipp Kiefer, Razvan Ionasec, Ingmar Voigt, Tommaso Mansi, Marcel Vollroth, Michael Hoebartner, Martin Misfeld, Friedrich-Wilhelm Mohr, Joerg Seeburger
organization:: Leipzig Heart Institute, Siemens Corporate Research
domain:: Medical Imaging, Computational Modeling, Biomechanics, Cardiology
link:: https://doi.org/10.3978/j.issn.2225-319x.2013.11.01
citations:: 20 (OpenAlex) · 25 (Semantic Scholar) — as of 14 October 2026

Article record — Europe PMC. Free full text available via PMC3857003.
Summary
A review written for cardiothoracic surgeons rather than for the imaging community - the bridge paper that explains what computational mitral valve models are for, to the people who would use them in theatre.
It sets out the taxonomy: geometrical models divide into rigid and dynamic, both reconstructed from echocardiographic or CT data, allowing analysis of valve morphology and dynamics through the cardiac cycle. Biomechanical models divide into structural models and fluid-structure interaction models, simulating the valve’s mechanics together with blood flow. The argument is that these represent substantial progress in diagnosing structural heart disease, because morphology and dynamics can now be studied in detail that was previously unavailable.
Data Points
- Review aimed at the surgical audience, co-authored with the Heart Center Leipzig mitral team
- Taxonomy of geometrical models: rigid versus dynamic, both reconstructed from echo or CT
- Taxonomy of biomechanical models: structural versus fluid-structure interaction (FSI)
- Positions computational modelling as substantive progress in structural heart disease diagnosis
- Frames the open problem plainly: the complexity of mitral valve anatomy and function is not yet fully understood
Reference
Annals of Cardiothoracic Surgery 2(6), 2013. doi:10.3978/j.issn.2225-319x.2013.11.01 · PubMed 24349983
20-25 citations (OpenAlex / Semantic Scholar, October 2026)
Part of the complete record in Scientific Publications - Peer-Reviewed Research Record.

